人 ACVR1C (NM_001111031) cDNA克隆

基本信息

Accession: NM_001111031
基因名称: ACVR1C
基因别名: ALK7; ACVRLK7
基因描述: Homo sapiens activin A receptor, type IC (ACVR1C), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1332 (查看编码区序列)
翻译后氨基酸长度: 443 (查看氨基酸序列)
Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2), also known as tALK7, has a shorter N-terminus when compared to isoform 1, and lacks part of the activin receptor-binding domain.

订购信息

产品编号 产品名称 载体 规格 价格
G115099 人 ACVR1C (NM_001111031) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ACVR1C (NM_145259) cDNA克隆 transcript variant 1
人 ACVR1C (NM_001111031) cDNA克隆 transcript variant 2
人 ACVR1C (NM_001111032) cDNA克隆 transcript variant 3
人 ACVR1C (NM_001111033) cDNA克隆 transcript variant 4

基因简介

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

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