人 KLF7 (NM_001270942) cDNA克隆

基本信息

Accession: NM_001270942
基因名称: KLF7
基因别名: UKLF
基因描述: Homo sapiens Kruppel-like factor 7 (ubiquitous) (KLF7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 693 (查看编码区序列)
翻译后氨基酸长度: 230 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate splice site in the coding region that results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G108360 人 KLF7 (NM_001270942) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KLF7 (NM_003709) cDNA克隆 transcript variant 1
人 KLF7 (NM_001270942) cDNA克隆 transcript variant 2
人 KLF7 (NM_001270943) cDNA克隆 transcript variant 3
人 KLF7 (NM_001270944) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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