人 KLF7 (NM_001270944) cDNA克隆

Accession: NM_001270944
基因名称: KLF7
基因别名: UKLF
基因描述: Homo sapiens Kruppel-like factor 7 (ubiquitous) (KLF7), transcript variant 4, mRNA.
种属: Human
CDS区长度: 825 (查看编码区序列)
翻译后氨基酸长度: 274 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4) has a distinct N-terminus and is shorter than isoform 1.
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G108362 人 KLF7 (NM_001270944) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]