人 KLF11 (NM_001177716) cDNA克隆

Accession: NM_001177716
基因名称: KLF11
基因别名: FKLF; FKLF1; MODY7; TIEG2; Tieg3
基因描述: Homo sapiens Kruppel-like factor 11 (KLF11), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1488 (查看编码区序列)
翻译后氨基酸长度: 495 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
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G116170 人 KLF11 (NM_001177716) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]