人 KLF11 (NM_003597) cDNA克隆

Accession: NM_003597
基因名称: KLF11
基因别名: FKLF; FKLF1; MODY7; TIEG2; Tieg3
基因描述: Homo sapiens Kruppel-like factor 11 (KLF11), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1539 (查看编码区序列)
翻译后氨基酸长度: 512 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G116172 人 KLF11 (NM_003597) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]