人 APBB3 (NM_133174) cDNA克隆

Accession: NM_133174
基因名称: APBB3
基因别名: SRA; FE65L2
基因描述: Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 3 (APBB3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1455 (查看编码区序列)
翻译后氨基酸长度: 484 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks tandem 6 nt and 21 nt miniexons in the coding region but maintains the same reading frame as transcript variant 4. As a result, variant 1 encodes isoform a which lacks 9 internal aa as compared to isoform d encoded by transcript variant 4.
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G111611 人 APBB3 (NM_133174) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]