人 IKZF3 (NM_001284516) cDNA克隆

基本信息

Accession: NM_001284516
基因名称: IKZF3
基因别名: AIO; AIOLOS; ZNFN1A3
基因描述: Homo sapiens IKAROS family zinc finger 3 (Aiolos) (IKZF3), transcript variant 16, mRNA.
种属: Human
CDS区长度: 789 (查看编码区序列)
翻译后氨基酸长度: 262 (查看氨基酸序列)
Transcript Variant: This variant (16) represents use of an alternate promoter and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (14) with a shorter N-terminus, compared to isoform 1. Variants 14, 15, and 16 encode the same isoform (14).

订购信息

产品编号 产品名称 载体 规格 价格
G111898 人 IKZF3 (NM_001284516) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IKZF3 (NM_012481) cDNA克隆 transcript variant 1
人 IKZF3 (NM_001257411) cDNA克隆 transcript variant 10
人 IKZF3 (NM_001257412) cDNA克隆 transcript variant 11
人 IKZF3 (NM_001257413) cDNA克隆 transcript variant 12
人 IKZF3 (NM_001257414) cDNA克隆 transcript variant 13
人 IKZF3 (NM_001284514) cDNA克隆 transcript variant 14
人 IKZF3 (NM_001284515) cDNA克隆 transcript variant 15
人 IKZF3 (NM_001284516) cDNA克隆 transcript variant 16
人 IKZF3 (NM_183228) cDNA克隆 transcript variant 2
人 IKZF3 (NM_183229) cDNA克隆 transcript variant 3
人 IKZF3 (NM_183230) cDNA克隆 transcript variant 4
人 IKZF3 (NM_183231) cDNA克隆 transcript variant 5
人 IKZF3 (NM_183232) cDNA克隆 transcript variant 6
人 IKZF3 (NM_001257408) cDNA克隆 transcript variant 7
人 IKZF3 (NM_001257409) cDNA克隆 transcript variant 8
人 IKZF3 (NM_001257410) cDNA克隆 transcript variant 9

基因简介

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

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