AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]
Accession: | NM_001278160 |
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基因名称: | AKT1S1 |
基因别名: | Lobe; PRAS40 |
基因描述: | Homo sapiens AKT1 substrate 1 (proline-rich) (AKT1S1), transcript variant 5, mRNA. |
种属: | Human |
CDS区长度: | 771 (查看编码区序列) |
翻译后氨基酸长度: | 256 (查看氨基酸序列) |
Transcript Variant: | This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, 4, and 5 encode the same isoform (b). |
人 AKT1S1 (NM_032375) cDNA克隆 | transcript variant 1 |
人 AKT1S1 (NM_001098632) cDNA克隆 | transcript variant 2 |
人 AKT1S1 (NM_001098633) cDNA克隆 | transcript variant 3 |
人 AKT1S1 (NM_001278159) cDNA克隆 | transcript variant 4 |
人 AKT1S1 (NM_001278160) cDNA克隆 | transcript variant 5 |
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]