人 AKT2 (NM_001243028) cDNA克隆

基本信息

Accession: NM_001243028
基因名称: AKT2
基因别名: PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
基因描述: Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1260 (查看编码区序列)
翻译后氨基酸长度: 419 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks an alternate exon in the 5' coding region, and initiates translation at a downstream AUG. This results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G116973 人 AKT2 (NM_001243028) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AKT2 (NM_001626) cDNA克隆 transcript variant 1
人 AKT2 (NM_001243027) cDNA克隆 transcript variant 2
人 AKT2 (NM_001243028) cDNA克隆 transcript variant 3

基因简介

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]

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