人 AKT2 (NM_001626) cDNA克隆

Accession: NM_001626
基因名称: AKT2
基因别名: PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
基因描述: Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1446 (查看编码区序列)
翻译后氨基酸长度: 481 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G116971 人 AKT2 (NM_001626) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]