人 RCHY1 (NM_015436) cDNA克隆

Accession: NM_015436
基因名称: RCHY1
基因别名: ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996
基因描述: Homo sapiens ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase (RCHY1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 786 (查看编码区序列)
翻译后氨基酸长度: 261 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1, also known as Pirh2A).
产品编号 产品名称 载体 规格 价格
G115447 人 RCHY1 (NM_015436) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]