人 RCHY1 (NM_001278536) cDNA克隆

基本信息

Accession: NM_001278536
基因名称: RCHY1
基因别名: ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996
基因描述: Homo sapiens ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase (RCHY1), transcript variant 6, mRNA.
种属: Human
CDS区长度: 666 (查看编码区序列)
翻译后氨基酸长度: 221 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (4) is shorter, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G115448 人 RCHY1 (NM_001278536) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RCHY1 (NM_015436) cDNA克隆 transcript variant 1
人 RCHY1 (NM_001009922) cDNA克隆 transcript variant 3
人 RCHY1 (NM_001278536) cDNA克隆 transcript variant 6
人 RCHY1 (NM_001278537) cDNA克隆 transcript variant 7
人 RCHY1 (NM_001278538) cDNA克隆 transcript variant 8
人 RCHY1 (NM_001278539) cDNA克隆 transcript variant 9

基因简介

The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]

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