人 ABCB9 (NM_203444) cDNA克隆

Accession: NM_203444
基因名称: ABCB9
基因别名: TAPL; EST122234
基因描述: Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 9 (ABCB9), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2052 (查看编码区序列)
翻译后氨基酸长度: 683 (查看氨基酸序列)
Transcript Variant: This variant (4, also known as 12B) has an alternate 3' exon and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (4) has a distinct and shorter C-terminus, compared to isoform 1.
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G118338 人 ABCB9 (NM_203444) cDNA克隆 pDONR223 2ug质粒 点击询价

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]