人 ABCB8 (NM_001282292) cDNA克隆

基本信息

Accession: NM_001282292
基因名称: ABCB8
基因别名: MABC1; M-ABC1; EST328128
基因描述: Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2082 (查看编码区序列)
翻译后氨基酸长度: 693 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G124936 人 ABCB8 (NM_001282292) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABCB8 (NM_001282291) cDNA克隆 transcript variant 1
人 ABCB8 (NM_007188) cDNA克隆 transcript variant 2
人 ABCB8 (NM_001282292) cDNA克隆 transcript variant 3
人 ABCB8 (NM_001282293) cDNA克隆 transcript variant 4

基因简介

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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