人 ABCB8 (NM_001282293) cDNA克隆

基本信息

Accession: NM_001282293
基因名称: ABCB8
基因别名: MABC1; M-ABC1; EST328128
基因描述: Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1893 (查看编码区序列)
翻译后氨基酸长度: 630 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks two alternate exons in the 5' coding region and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (d) is shorter and has a distinct N-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G124937 人 ABCB8 (NM_001282293) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABCB8 (NM_001282291) cDNA克隆 transcript variant 1
人 ABCB8 (NM_007188) cDNA克隆 transcript variant 2
人 ABCB8 (NM_001282292) cDNA克隆 transcript variant 3
人 ABCB8 (NM_001282293) cDNA克隆 transcript variant 4

基因简介

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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