人 BAG2 (NM_004282) cDNA克隆

Accession: NM_004282
基因名称: BAG2
基因别名: BAG-2; dJ417I1.2
基因描述: Homo sapiens BCL2-associated athanogene 2 (BAG2), mRNA.
种属: Human
CDS区长度: 636 (查看编码区序列)
翻译后氨基酸长度: 211 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G123979 人 BAG2 (NM_004282) cDNA克隆 pDONR223 2ug质粒 点击询价

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]