人 BAG1 (NM_001172415) cDNA克隆

基本信息

Accession: NM_001172415
基因名称: BAG1
基因别名: HAP; BAG-1; RAP46
基因描述: Homo sapiens BCL2-associated athanogene (BAG1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 693 (查看编码区序列)
翻译后氨基酸长度: 230 (查看氨基酸序列)
Transcript Variant: This transcript (1) encodes multiple isoforms due to the use of alternative translation initiation codons. The longest isoform (BAG-1L or p50) is derived from an upstream non-AUG (CUG) start codon, while three shorter isoforms are derived from downstream AUG start codons. The most abundant of the shorter isoforms (BAG-1S, also known as p33 or p36), which is derived from the second downstream AUG start codon, is represented in this RefSeq.

订购信息

产品编号 产品名称 载体 规格 价格
G108913 人 BAG1 (NM_001172415) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BAG1 (NM_001172415) cDNA克隆 transcript variant 1
人 BAG1 (NM_004323) cDNA克隆 transcript variant 1

基因简介

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

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