人 ADAM8 (NM_001109) cDNA克隆

Accession: NM_001109
基因名称: ADAM8
基因别名: MS2; CD156
基因描述: Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2475 (查看编码区序列)
翻译后氨基酸长度: 824 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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G124497 人 ADAM8 (NM_001109) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]