人 ADAM8 (NM_001164490) cDNA克隆

基本信息

Accession: NM_001164490
基因名称: ADAM8
基因别名: MS2; CD156
基因描述: Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2202 (查看编码区序列)
翻译后氨基酸长度: 733 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks three alternate exons and uses an alternate splice site in the coding region, which results in a frameshifted segment, compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124499 人 ADAM8 (NM_001164490) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ADAM8 (NM_001109) cDNA克隆 transcript variant 1
人 ADAM8 (NM_001164489) cDNA克隆 transcript variant 2
人 ADAM8 (NM_001164490) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]

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