人 NCOA1 (NM_003743) cDNA克隆

Accession: NM_003743
基因名称: NCOA1
基因别名: SRC1; KAT13A; RIP160; F-SRC-1; bHLHe42; bHLHe74
基因描述: Homo sapiens nuclear receptor coactivator 1 (NCOA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4326 (查看编码区序列)
翻译后氨基酸长度: 1441 (查看氨基酸序列)
Transcript Variant: This variant (1), also known as SRC1a, encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G124721 人 NCOA1 (NM_003743) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]