人 NCOA1 (NM_147233) cDNA克隆

基本信息

Accession: NM_147233
基因名称: NCOA1
基因别名: SRC1; KAT13A; RIP160; F-SRC-1; bHLHe42; bHLHe74
基因描述: Homo sapiens nuclear receptor coactivator 1 (NCOA1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 4323 (查看编码区序列)
翻译后氨基酸长度: 1440 (查看氨基酸序列)
Transcript Variant: This variant (3), also known as SRC(-Q), uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a protein (isoform 3) that lacks a single amino acid, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124723 人 NCOA1 (NM_147233) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCOA1 (NM_003743) cDNA克隆 transcript variant 1
人 NCOA1 (NM_147223) cDNA克隆 transcript variant 2
人 NCOA1 (NM_147233) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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