人 NCOA6 (NM_001242539) cDNA克隆

Accession: NM_001242539
基因名称: NCOA6
基因别名: NRC; AIB3; ASC2; PRIP; TRBP; RAP250
基因描述: Homo sapiens nuclear receptor coactivator 6 (NCOA6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3213 (查看编码区序列)
翻译后氨基酸长度: 1070 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2, also known as NCOA6-beta) missing an internal protein segment compared to isoform 1.
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G139956 人 NCOA6 (NM_001242539) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]