人 ABCC4 (NM_001105515) cDNA克隆

基本信息

Accession: NM_001105515
基因名称: ABCC4
基因别名: MRP4; MOATB; MOAT-B; EST170205
基因描述: Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2580 (查看编码区序列)
翻译后氨基酸长度: 859 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region, compared to variant 1, resulting in a protein (isoform 2) with a shorter, distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G120901 人 ABCC4 (NM_001105515) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABCC4 (NM_005845) cDNA克隆 transcript variant 1
人 ABCC4 (NM_001105515) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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