人 ABCC6 (NM_001079528) cDNA克隆

基本信息

Accession: NM_001079528
基因名称: ABCC6
基因别名: ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056
基因描述: Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 300 (查看编码区序列)
翻译后氨基酸长度: 99 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks much of the coding region and represents a distinct 3' UTR compared to variant 1. The encoded protein (isoform 2) is much shorter and has a distinct C-terminus compared to isoform 1. The encoded protein is not a transporter, but is thought to play a role in protecting hepatocytes during chronic hepatitis B virus infection.

订购信息

产品编号 产品名称 载体 规格 价格
G124785 人 ABCC6 (NM_001079528) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ABCC6 (NM_001171) cDNA克隆 transcript variant 1
人 ABCC6 (NM_001079528) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]

相关产品