人 KLF8 (NM_001159296) cDNA克隆

基本信息

Accession: NM_001159296
基因名称: KLF8
基因别名: BKLF3; ZNF741
基因描述: Homo sapiens Kruppel-like factor 8 (KLF8), transcript variant 2, mRNA.
种属: Human
CDS区长度: 774 (查看编码区序列)
翻译后氨基酸长度: 257 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks an exon in the 3' coding region that causes a frameshift compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G127892 人 KLF8 (NM_001159296) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KLF8 (NM_007250) cDNA克隆 transcript variant 1
人 KLF8 (NM_001159296) cDNA克隆 transcript variant 2

基因简介

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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