人 ABCC12 (NM_033226) cDNA克隆

Accession: NM_033226
基因名称: ABCC12
基因别名: MRP9
基因描述: Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 12 (ABCC12), mRNA.
种属: Human
CDS区长度: 4080 (查看编码区序列)
翻译后氨基酸长度: 1359 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G167606 人 ABCC12 (NM_033226) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]